solved: In addition to measuring muscle contraction and neurotransmitter…


In addition to measuring muscle contraction and neurotransmitter…In addition to measuring muscle contraction and neurotransmitter release, it is also possible to use electrodes to measure the conduction of action potentials along a motor neuron. IMPORTANT – remember we are artificially generating an action potential in the motor neuron, so the only site of synaptic transmission is the NMJ. Given the mechanism of action of the following venoms, predict what effect each of them would have had on the conduction of action potentials along the motor neuron in this experiment. Remember to justify your answer.  Redback spider (Latrodectus hasseltii) – contains a toxin which forms pores in the cell membrane of neurons, allowing the influx of Ca2+ into the nerve terminalBlue-ringed octopus (Hapalochlaena lunulata) – contains a toxin which blocks voltage-gated Na+ channelsTiger snake (Notechis scutatus) – contains a toxin which prevents ACh binding to nAChRs on muscle fibres BiologySciencePhysiology HBS 202

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