The patient is 40 years old, has no known medical issues, and is…The patient is 40 years old, has no known medical issues, and is not on any medication therapy. He is suffering from moderate back pain as a result of his injury. He was given Co-codamol 15/500, which contains 15 mg codeine phosphate and 500 mg paracetamol per tablet and is taken 2 tablets qds for seven days. 1) Simply compare the pharmacological mechanisms of both of this medicine’s constituents. In your response, highlight similarities and contrasts to explain why this medicine combination was utilised. 2) The patient has also been informed that he may need to take Senokot in addition to Co-codamol. Explain why this is necessary. 3) Codeine is frequently referred as a “semi-synthetic.” Explain what this indicates and why it only applies to this drug in part.4) Based on their chemical properties, compare the affinities of morphine and codeine for their biological targets. After a week, the patient returns to the pharmacy to report that the doctor won’t let him have any more of this drug and that he’s been prescribed dexketoprofen 25 mg every 8 hours alternatively. 5) How would you explain to the patient why his initial medicine is just for a limited period of time?6) The chemical structure of dexketoprofen is shown below. Assign the stereochemical absolute configuration of this drug, detailing the steps taken for the assignment for this structure.Image transcription textO CO2H dexketoprofen… Show more 7) Outline the medicinal effects of dexketoprofen and how they are related to its chemical structure. A few days later, the patient comes to the pharmacy, complaining that the new prescription isn’t doing enough to relieve her pain. He claims that when he suffered similar back pain following a sporting accident around ten years ago, he used to buy Voltarol Pain-eze (Diclofenac potassium) tablets over the counter, which significantly helped. He has been informed that items are no longer available for purchase and requests that you explain why. He is especially concerned if these medications were dangerous in any manner. 8) How would you counsel the patient? BiologySciencePharmacology PHR 2010
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